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Arthrosemid vs. Steroid for the Management Knee Osteoarthritis
Sponsor: Cappagh National Orthopaedic Hospital
Summary
This study will be a randomised control trial of the use of intra-articular Arthrosamid® a novel intraarticular hydrogel vs. standard of care (steroid and local anaesthetic) for the non-operative management of knee osteoarthritis.
Official title: A Randomised Control Trial of the Use of an Intraarticular Hydrogel Arthrosemid® vs. Steroid for the Non-operative Management of Moderate to Severe Osteoarthritis
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-03
Completion Date
2027-09
Last Updated
2026-03-27
Healthy Volunteers
Yes
Interventions
Arthrosamid® 2.5% iPAAG injectable implant
Arthrosamid is a non-biodegradable, 2.5% polyacrylamide hydrogel (iPAAG) injection designed as a long-lasting, non-surgical treatment for knee osteoarthritis. It acts as a synovial implant that provides cushioning, reduces pain, and improves mobility for up to 3-4 years, often delaying the need for knee replacement surgery.
Steroid Drug
dexamethasone 8mg, methylprednisolone 80mg and bupivacaine 5ml 0.25%, intra articular injection
Locations (1)
Cappagh National Orthopaedic Hospital
Dublin, Dublin, Ireland