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RECRUITING
NCT07490691
NA

Painhunting Therapy for Interpersonal Loss-Related Depression

Sponsor: Painhunting LLP

View on ClinicalTrials.gov

Summary

This pilot randomized controlled trial evaluates the efficacy of Painhunting therapy, a brief structured psychotherapy, for adults with significant interpersonal loss and comorbid depressive symptoms in Kazakhstan. Seventy-two participants will be randomly assigned to receive either immediate Painhunting therapy (3 sessions over 3-4 weeks) or a 4-week waitlist control condition. Therapy is delivered in-person in Astana or remotely via secure video conferencing (Zoom). Therapy sessions will be delivered by five trained Painhunting practitioners under the supervision of the Principal Investigator. The primary outcomes are changes in depression severity (PHQ-9) and complicated grief symptoms (ICG) from baseline to post-treatment. Secondary outcomes include anxiety, PTSD symptoms, and functional disability. All waitlist participants receive treatment after the waiting period.

Official title: Efficacy of Painhunting Therapy for Interpersonal Loss-Related Depression: A Waitlist-Controlled Randomized Pilot Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

72

Start Date

2026-03-23

Completion Date

2026-10-30

Last Updated

2026-04-07

Healthy Volunteers

No

Interventions

BEHAVIORAL

Painhunting Therapy

Painhunting therapy is a structured psychotherapeutic intervention designed to identify emotionally significant past experiences associated with current psychological distress and facilitate emotional processing of these experiences. The intervention consists of three individual sessions delivered over 3-4 weeks by trained practitioners.

Locations (1)

Painhunting Research Center

Astana, Astana, Kazakhstan