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Levetiracetam Three Times Daily in Epilepsy
Sponsor: Waad Alkathiri
Summary
The purpose of this clinical trial is to evaluate the efficacy and tolerability of Levetiracetam administered three times daily in patients with epilepsy. The primary objective is to investigate whether orally administered Levetiracetam three times daily dosing is superior in seizure-free days compared to standard twice-daily dosing in patients with epilepsy. Key questions include: * Does LEV improve seizure control, as measured by seizure-free days? * What adverse events or safety concerns are observed with LEV treatment? Participants will receive Levetiracetam administered three times daily during the treatment phase. The study will use a self-matched, pre-post design in which each participant serves as their own control. Baseline seizure activity and safety data will be collected prior to LEV initiation and compared with data obtained during the treatment period. Participants will attend scheduled clinic visits for efficacy and safety evaluations and will maintain a daily diary to record seizure frequency and any treatment-related events.
Official title: Evaluating Efficacy and Tolerability of Three Times Daily Levetiracetam in Epilepsy Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-10-01
Completion Date
2028-12-30
Last Updated
2026-03-24
Healthy Volunteers
No
Conditions
Interventions
Levetiracetam
Levetiracetam oral (500mg - 1000 mg) tablet three times a day for 12 months
Locations (1)
King Saud University
Riyadh, Riyadh Region, Saudi Arabia