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Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment
Sponsor: University of Liege
Summary
Impact of nicotine gingival intoxication on the clinical outcomes after periodontitis non surgical treatment
Official title: Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment, in Conventional and Non Smokers: a Controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2025-01-06
Completion Date
2029-06
Last Updated
2026-03-24
Healthy Volunteers
No
Interventions
periodontal non-surgical treatment
The procedure will consist of non-surgical periodontal treatment (NSPT), consisting of the removal of supra- and subgingival plaque using ultrasonic instruments. Prior to the NSPT, all unstimulated saliva will be collected using Eppendorf. During local anesthesia for the NSPT, a gingival tissue biopsy will be performed using a 2mm wide and 4mm deep punch in the maxillary retromolar area behind the last tooth in the arch.
Locations (1)
Departement of periodontology, buccal surgery and implantology- Uliège, Belgium
Liège, Liege, Belgium