Clinical Research Directory
Browse clinical research sites, groups, and studies.
Conduction System Pacing vs. Biventricular Pacing for Cardiac Resynchronization Therapy
Sponsor: Rigshospitalet, Denmark
Summary
The NORDIC-CSP trial is an investigator-initiated, blinded, nordic RCT aimed at evaluating whether using direct pacing of the HIS bundle (HIS)-pacing or left bundle branch (LBB) pacing is superior to conventional biventricular pacing in reducing the incidence of the composite endpoint of death and non-planned HF hospitalization. The study will be conducted in the 4 CRT-centres in Denmark and 6-8 centres from countries Sweden, Norway and Finland.
Official title: Nordic-CSP - a Randomized Nordic Study - Is Conduction System Pacing Superior Compared to Conventional BIV-CRT in Reducing the Death or Heart Failure-related Hospitalization in Patients With Heart Failure and Bundle Branch Block?
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
1100
Start Date
2026-03-01
Completion Date
2031-07-01
Last Updated
2026-03-25
Healthy Volunteers
No
Interventions
HIS or LBBB -CRT
HIs pacing og LBB pacing at the implanteres discretion
Conventional BiV-CRT
An LV-lead in a side-branch of the coronary sinus
Locations (4)
Dept. of Cardiology, Aarhus University Hospital, Aarhus
Aarhus, Denmark
Dept of Cardiology, Meilahti Hospital, Helsinki
Helsinki, Finland
Haukeland Universitetssykehus
Bergen, Norway
Sahlgrenska University Hospital
Gothenburg, Sweden