Clinical Research Directory

Inclusion Criteria: * Full-time college students aged 18 to 25 years old. * Healthy, with no history of major cardiovascular, respiratory, neurological, or endocrine diseases. * No exercise contraindications or injuries, capable of safely completing moderate-intensity running (treadmill, outdoor road, and grass running). * No recent major life events affecting physiological or psychological status (e.g., severe insomnia, anxiety, depression, or extreme fatigue). * No use of medications or supplements affecting heart rate, blood pressure, mood, or attention within the past week. * Normal or corrected-to-normal vision, capable of completing computerized cognitive tasks (e.g., Stroop, Go/No-Go, PVT). * Able to comprehend and truthfully complete psychological scales. * Voluntary participation and signed informed consent form. Exclusion Criteria: * Current or past diagnosis of severe cardiovascular disease (e.g., myocardial infarction, severe arrhythmia, uncontrolled hypertension). * Severe respiratory disease (e.g., severe asthma, COPD) or recent acute respiratory infection within the past month. * History of neurological disease or brain injury (e.g., epilepsy, recent concussion) affecting safety or cognitive task performance. * Endocrine or metabolic diseases (e.g., uncontrolled thyroid disease, severe diabetes) affecting cortisol or metabolic measurements. * Recent diagnosis or psychiatric treatment for severe psychological disorders within the past month. * Use of drugs or supplements affecting heart rate, blood pressure, cortisol, or attention within the past 7 days. * Currently pregnant or lactating. * Acute illness within the past 48 hours (e.g., fever, acute gastroenteritis). * Severe bleeding tendencies, blood disorders, or contraindications to blood/saliva sampling. * Recent substance use interference, such as heavy drinking or substance dependence within the past 2 weeks. * Inability to meet pre-experiment control requirements (e.g., avoiding caffeine, tobacco, or heavy exercise). * Inability to complete computerized tasks due to poor vision or lack of familiarity with keyboard/mouse. * Acute or chronic injuries hindering the safe completion of running intervention (e.g., recent lower limb injury). * Participation in similar HIT or environmental intervention studies within the past 3 months. * Unable to understand research procedures or unwilling to sign the informed consent form.