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Anderson-Fabry Disease Fitness Improvement Training
Sponsor: General University Hospital, Prague
Summary
This study will evaluate physical function, cardiorespiratory fitness, muscle strength, and quality of life in patients with Fabry disease and assess the effects of a 12-week physiotherapy-led exercise programme. Participants will be non-randomly assigned to an exercise intervention group or a control group receiving no study-specific exercise intervention. The intervention group will be assessed at baseline, immediately after the 12-week intervention, and 12 months after baseline. The control group will be assessed at baseline and 12 months after baseline.
Official title: Anderson-Fabry Disease Fitness Improvement Training: A-FAD-FIT
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-10-06
Completion Date
2028-12-31
Last Updated
2026-09-21
Healthy Volunteers
No
Conditions
Interventions
Physiotherapy exercise programe
A 12-week physiotherapy-led exercise programme consisting of one supervised session and two home-based exercise sessions per week. Supervised sessions include a brief aerobic warm-up followed by strengthening exercises using body weight and resistance bands. The programme also includes a progressive increase in daily ambulatory physical activity, monitored primarily by daily step count. Adherence is monitored using exercise diaries and regular follow-up during supervised sessions.
Locations (1)
General University Hospital
Prague, Czechia