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RECRUITING
NCT07496905
NA

The Effect of the Valsalva Maneuver in Endometrial Biopsy: A Randomized Controlled Trial

Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

View on ClinicalTrials.gov

Summary

Endometrial sampling with a pipelle is a common procedure used to collect a small sample from the lining of the uterus. During the procedure, the cervix is sometimes held with a surgical instrument called a tenaculum, which may cause pain and anxiety for some women. The Valsalva maneuver is a simple technique in which a person takes a deep breath and pushes as if trying to exhale forcefully. This increases pressure inside the abdomen and may help keep the uterus and cervix more stable during the procedure. This study aims to compare pipelle sampling performed with the Valsalva maneuver to the standard method using a tenaculum. The study will evaluate whether the Valsalva maneuver can reduce pain and anxiety while maintaining procedure success and improving patient satisfaction.

Official title: The Effect of the Valsalva Maneuver on Pain and Procedure Success in Endometrial Biopsy: A Randomized Controlled Trial

Key Details

Gender

FEMALE

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2025-01-01

Completion Date

2026-12-01

Last Updated

2026-03-27

Healthy Volunteers

Yes

Interventions

PROCEDURE

endometrial biopsy

Endometrial sampling performed using a pipelle cannula.

PROCEDURE

Tenaculum Application

Application of a tenaculum to the cervix to stabilize it during endometrial biopsy.

PROCEDURE

Valsalva Maneuver

Patients perform the Valsalva maneuver during endometrial biopsy to reduce perceived pain.

Locations (1)

Cemil Tascioglu City Hospital

Istanbul, Turkey (Türkiye)