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NOT YET RECRUITING
NCT07497074
PHASE2

JSKN033 Combination Therapy in Subjects With Advanced Cervical Cancer

Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if the therapy of JSKN033 plus chemotherapy with or with bevacizumab is safe to treat patients with advanced cervical cancer. It will also learn about the antitumor activity and pharmacokinetic/ pharmacodynamic profiles of this therapy.

Official title: A Phase II Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Combination With Platinum-Based Chemotherapy With or Without Bevacizumab in Patients With Advanced Cervical Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

78

Start Date

2026-04

Completion Date

2028-06

Last Updated

2026-03-27

Healthy Volunteers

No

Conditions

Interventions

DRUG

JSKN033

JSKN033 in combination with platinum-based chemotherapy with or without bevacizumab at selected dose levels according to protocol

DRUG

Platinum

JSKN033 in combination with platinum-based chemotherapy with or without bevacizumab at selected dose levels according to protocol

DRUG

Bevacizumab

JSKN033 in combination with platinum-based chemotherapy with or without bevacizumab at selected dose levels according to protocol

Locations (2)

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China