Clinical Research Directory

Inclusion Criteria: * Subject is a candidate for surgical repair of pelvic organ prolapse by ProGYNious implant according to the indication of the product under evaluation * Symptomatic pelvic organ prolapse with POP-Q \>= 2 * Age \>18 years and ≤ 80years * Subject is willing and able to cooperate with follow-up examinations * Subject has been informed of the study procedures and the treatment and has signed an informed consent form Exclusion Criteria: * previous or concurrent cancer which may affect the successful treament with laparoscopic mesh * known or suspected hypersensitivity to ProGYNious mesh or a component of ProGYNious mesh (Polypropylene) * known severe osteoporosis * pregnancy, suspected pregnancy and breastfeeding * bleeding of unknown cause in the genital area * previously irradiated patients in the pelvic area * drug or medication abuse, medical, psychological or social circumstances that could affect the patient's participation in the study or the evaluation of the study results * Any previous interventions with surgical mesh for pelvic organ prolapse and/or urinary incontinence * Unable to understand study requirements or is unable to comply with follow-up schedule * Contraindicated according to the instruction for use of the device * patients with an increased risk of infection or impaired wound healing (e.g. Diabetes mellitus with HbA1c \>10, systemic autoimmune diseases, etc.) * concomitant Sling/TVT procedure * life expectancy lower than follow-up period (e.g. ASA 4) * non-symptomatic pelvic organ prolapse * chronic pain syndrome * chronic respiratory disease (e.g. COPD, chronic cough)