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Exercise for the Treatment of Cancer-Related Sarcopenia
Sponsor: State University of Londrina
Summary
Our primary objective is to assess the effects of exercise on cancer-related sarcopenia and its hallmarks, including muscle strength, muscle mass, and physical performance. The secondary objectives are to examine exercise adherence and the effects of exercise on health-related quality of life (QoL), cancer-related fatigue, and sleep quality. Additionally, we will explore the effects of exercise on bone and fat mass as secondary outcomes.
Official title: Exercise for the Treatment of Cancer-Related Sarcopenia: a Randomised Controlled Trial.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
78
Start Date
2026-04-01
Completion Date
2028-12
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Interventions
Multimodal, supervised exercise training
The multicomponent exercise intervention included a 10-minute warm-up consisting of balance, coordination, and stretching exercises. The main component was resistance training targeting major upper and lower body muscle groups to improve muscle strength and mass. Six to eight exercises were performed using body weight, elastic bands, and dumbbells. Training progression was achieved by increasing load, repetitions, and/or sets, guided by the 0-10 Borg rating of perceived exertion when health status permitted. The aerobic component consisted of walking progressing to beginner-level running, using short running intervals (50-100 m) interspersed with walking until longer continuous distances were achieved. Heart rate was monitored throughout the aerobic session.
Locations (1)
State University of Londrina
Londrina, Paraná, Brazil