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Effect of Morus Nigra Mouthwash on Gingivitis Treatment
Sponsor: Inonu University
Summary
The aim of this study is to evaluate the clinical, microbiological, and biochemical effects of Morus nigra (black mulberry) mouthwash when used as an adjunct to non-surgical periodontal treatment (scaling and root planing - SRP) in patients with generalized gingivitis. Participants will be randomly assigned to two groups: one receiving SRP only, and the other receiving SRP plus Morus nigra mouthwash twice daily for 14 days. Clinical parameters, cytokine levels in gingival crevicular fluid (TNF-alpha, IL-1beta, IL-10), and subgingival bacterial load will be assessed at baseline, 1 month, and 3 months.
Official title: Evaluation of the Efficacy of Morus Nigra Mouthwash as an Adjunct to Scaling and Root Planing in the Treatment of Gingivitis: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-01-15
Completion Date
2026-07-15
Last Updated
2026-03-30
Healthy Volunteers
No
Conditions
Interventions
Scaling and Root Planing
Mechanical removal of dental plaque and calculus from the tooth surfaces
Morus Nigra Mouthwash
Morus nigra extract based mouthwash, used 2 times a day for 14 days
Locations (1)
Inonu University Faculty of Dentistry
Battalgazi, Malatya, Turkey (Türkiye)