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Analgesic Equivalence of NSAIDs and Tramadol in Acute Postoperative Pain Following Minimally Invasive Surgery
Sponsor: ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Summary
This pilot randomised controlled trial compared the analgesic equivalence of three intravenous premedication regimens - tramadol 150 mg, ketorolac 60 mg, and diclofenac 150 mg - in adult patients undergoing elective minimally invasive surgery under balanced general anaesthesia. The primary outcome was postoperative pain intensity measured using the Numerical Rating Scale (NRS 0-10) at recovery room arrival and at 30, 60, and 90 minutes thereafter.
Official title: Analgesic Equivalence of NSAIDs and a Weak Opioid in Acute Postoperative Pain Following Minimally Invasive Surgery Under Balanced General Anaesthesia: A Pilot Randomised Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-06-20
Completion Date
2024-07-26
Last Updated
2026-07-10
Healthy Volunteers
No
Conditions
Interventions
Tramadol
Tramadol 150 mg IV, single dose, administered in 100 mL 0.9% saline 45 minutes before skin incision.
Ketorolac
Ketorolac 60 mg IV, single dose, administered in 100 mL 0.9% saline 45 minutes before skin incision.
Diclofenac
Diclofenac 150 mg IV, single dose, administered in 100 mL 0.9% saline 45 minutes before skin incision.
Locations (1)
Hospital Regional "General Ignacio Zaragoza," ISSSTE
Mexico City, Mexico City, Mexico