Clinical Research Directory

Inclusion Criteria: * Women ≥ 18 years of age. * Patients evaluated by a pelvic floor specialist (either urogynecologist or urologist) at the University of Miami with plans to undergo urethral bulking with Bulkamid for stress urinary incontinence or mixed urinary incontinence (stress predominant). * Negative testing for UTI in pre-procedural work-up (including either negative urine culture or urine dip negative for infection). * Post-void residual volume of 150 mL or less (measured by either catheterization or bladder scan) * Fluent in English or Spanish * Able and willing to provide informed consent Exclusion Criteria: * Contraindications to both oral antibiotics including antibiotic allergies or significant renal disease (GFR \<30) * Patient undergoing additional pelvic organ prolapse procedures or other urologic procedures concomitantly * Recurrent UTIs, defined as 3 or more UTIs within the past 12 months or 2 UTIs within the past 6 months * Patients currently taking daily antibiotic prophylaxis for any reason * Pelvic organ prolapse stage greater than 2 * Patients with immunosuppression due to underlying medical conditions * Patients who are pregnant * Recent antibiotic treatment within one week of the procedure * Unable or unwilling to provide informed consent or complete study procedures