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Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin
Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Summary
The purpose of this study is to characterize the Influence of HDM1005 on gastric emptying and drug-drug interaction of HDM1005 and metformin, atorvastatin, warfarin, and digoxin in overweight/obese adult subjects.
Official title: A Phase I, Single-center, Open-Label, Single-Arm, Fixed-Sequence Study to Evaluate the Influence of HDM1005 on Gastric Emptying and Drug-Drug Interaction of HDM1005 and Metformin, Atorvastatin, Warfarin, and Digoxin in Overweight/Obese Adult Chinese Subjects
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2026-04-08
Completion Date
2027-06-02
Last Updated
2026-03-30
Healthy Volunteers
Yes
Conditions
Interventions
Acetaminophen
Single dose; Administered orally
Metformin
Single dose; Administered orally
Warfarin
Single dose; Administered orally
Atorvastatin
Single dose; Administered orally
Digoxin
Single dose; Administered orally
HDM1005 injection
Subcutaneous injection QW
Locations (1)
The Second Affiliated Hospital of Anhui Medical University
Hefei, China