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NOT YET RECRUITING
NCT07502001
PHASE1

Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin

Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

View on ClinicalTrials.gov

Summary

The purpose of this study is to characterize the Influence of HDM1005 on gastric emptying and drug-drug interaction of HDM1005 and metformin, atorvastatin, warfarin, and digoxin in overweight/obese adult subjects.

Official title: A Phase I, Single-center, Open-Label, Single-Arm, Fixed-Sequence Study to Evaluate the Influence of HDM1005 on Gastric Emptying and Drug-Drug Interaction of HDM1005 and Metformin, Atorvastatin, Warfarin, and Digoxin in Overweight/Obese Adult Chinese Subjects

Key Details

Gender

All

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

42

Start Date

2026-04-08

Completion Date

2027-06-02

Last Updated

2026-03-30

Healthy Volunteers

Yes

Interventions

DRUG

Acetaminophen

Single dose; Administered orally

DRUG

Metformin

Single dose; Administered orally

DRUG

Warfarin

Single dose; Administered orally

DRUG

Atorvastatin

Single dose; Administered orally

DRUG

Digoxin

Single dose; Administered orally

DRUG

HDM1005 injection

Subcutaneous injection QW

Locations (1)

The Second Affiliated Hospital of Anhui Medical University

Hefei, China