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RECRUITING
NCT07502924
NA

Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscle Health

Sponsor: Lindenwood University

View on ClinicalTrials.gov

Summary

This study will evaluate the effects of daily geranylgeraniol (GG) supplementation on muscular strength, body composition, and aerobic capacity in healthy, physically active men and women. Approximately 60 participants aged 30-60 years will be enrolled in a randomized, double-blind, placebo-controlled, parallel-group trial lasting 8 weeks. Participants will be assigned to receive either placebo, 150 mg GG, or 300 mg GG daily. Outcome measures will be assessed at baseline, week 4, and week 8 and include maximal strength (1RM bench press and leg press), fat-free mass, muscular endurance, aerobic capacity (VO2peak), and circulating biomarkers related to metabolism and health.

Official title: Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscular Strength, Body Composition, Sex Steroid Hormones and CoQ10 Levels in Healthy Men and Women

Key Details

Gender

All

Age Range

30 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2025-03-03

Completion Date

2026-08-01

Last Updated

2026-03-31

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Dietary Supplement - Placebo

Participants will ingest a placebo consisting of olive oil daily for 8 weeks. The supplement will be consumed with approximately 8 ounces of water at a consistent time each day.

DIETARY_SUPPLEMENT

Geranylgeraniol (150 mg)

Participants will ingest 150 mg of geranylgeraniol (GG) daily for 8 weeks. The supplement will be consumed with approximately 8 ounces of water at a consistent time each day.

DIETARY_SUPPLEMENT

Geranylgeraniol (300 mg)

Participants will ingest 300 mg of geranylgeraniol (GG) daily for 8 weeks. The supplement will be consumed with approximately 8 ounces of water at a consistent time each day.

Locations (1)

Lindenwood University Exercise and Performance Nutrition Laboratory

Saint Charles, Missouri, United States