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Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity
Sponsor: Radboud University Medical Center
Summary
Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).
Official title: Real-world Effectiveness and Dosing Patterns of Tirzepatide: A Multicentre Retrospective Observational Study in the Netherlands
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1700
Start Date
2026-04-01
Completion Date
2026-08-01
Last Updated
2026-03-31
Healthy Volunteers
No
Conditions
Interventions
Tirzepatide
Initiating treatment with tirzepatide
Locations (10)
NOK clinics
Amsterdam, Netherlands
NOK clinics
Arnhem, Netherlands
NOK clinics
Beverwijk, Netherlands
NOK clinics
Gouda, Netherlands
NOK clinics
Heerlen, Netherlands
NOK clinics
Hoogeveen, Netherlands
NOK clinics
Nieuwegein, Netherlands
NOK clinics
Terneuzen, Netherlands
NOK clinics
The Hague, Netherlands
NOK clinics
Venlo, Netherlands