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NOT YET RECRUITING
NCT07504172

Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

Sponsor: Radboud University Medical Center

View on ClinicalTrials.gov

Summary

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

Official title: Real-world Effectiveness and Dosing Patterns of Tirzepatide: A Multicentre Retrospective Observational Study in the Netherlands

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1700

Start Date

2026-04-01

Completion Date

2026-08-01

Last Updated

2026-03-31

Healthy Volunteers

No

Interventions

DRUG

Tirzepatide

Initiating treatment with tirzepatide

Locations (10)

NOK clinics

Amsterdam, Netherlands

NOK clinics

Arnhem, Netherlands

NOK clinics

Beverwijk, Netherlands

NOK clinics

Gouda, Netherlands

NOK clinics

Heerlen, Netherlands

NOK clinics

Hoogeveen, Netherlands

NOK clinics

Nieuwegein, Netherlands

NOK clinics

Terneuzen, Netherlands

NOK clinics

The Hague, Netherlands

NOK clinics

Venlo, Netherlands