Clinical Research Directory
Browse clinical research sites, groups, and studies.
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy
Sponsor: All India Institute of Medical Sciences, Bhubaneswar
Summary
RCT to compare the surgical success in patients undergoing external dacryocystorhinostomy with intraoperative Mitomycin-C (0.4 mg/ml) Vs Hyaluronic acid 1% (1ml) as adjuvant, To compare the complication rates and wound healing patterns in each group, To Compare change in tear MMP-9 levels from preoperative (within 1 week before surgery) to postoperative (6 weeks after surgery) , To compare the comfort levels of patients in each group.
Official title: Efficacy of Hyaluronic Acid as Intraoperative Adjuvant in External Dacryocystorhinostomy Compared to Mitomycin-C: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2026-04-01
Completion Date
2027-12-31
Last Updated
2026-03-31
Healthy Volunteers
No
Conditions
Interventions
Hyaluronic Acid (HA)
Hyaluronic Acid (HA)
Mitomycin -C
Mitomycin -C