Clinical Research Directory

Inclusion Criteria: 1. Meets the diagnostic criteria for chronic insomnia and simultaneously meets the diagnostic criteria for heart-kidney disharmony syndrome. 2. Pittsburgh Sleep Quality Index (PSQI) total score \> 7 points. 3. No insomnia treatment medication received within 2 weeks prior to the trial. 4. Age \> 18 years, gender unrestricted. 5. Voluntarily participates in this study, signs the informed consent form, and is willing to take medication on time and undergo follow-up visits. Exclusion Criteria: 1. Pregnant or lactating women. 2. Patients with an allergic constitution or hypersensitivity to multiple drugs. 3. Patients with primary diseases of the heart, liver, kidney, respiratory system, nervous system, hematopoietic system, or other systems, who are assessed by the investigator as unsuitable for participation in this study. 4. Patients with schizophrenia, bipolar affective disorder, major depressive disorder (Hamilton Depression Rating Scale HAMD17 \> 24 points), anxiety disorder (Hamilton Anxiety Rating Scale score ≥ 21 points), or other psychiatric disorders, as well as patients with senile dementia. 5. Patients with insomnia induced by drugs, strong coffee/tea, or other substances, or those who have taken Chinese or Western medicines for the treatment of insomnia within 2 weeks prior to enrollment. 6. History of alcohol or drug abuse. 7. Laboratory abnormalities: alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \> 2 times the upper limit of the normal range, or creatinine (Cr) \> the upper limit of the normal range. 8. Patients who have participated in any other clinical trial within the past 3 months. 9. Patients whom the investigator considers unsuitable for participation in this clinical trial.