Clinical Research Directory
Browse clinical research sites, groups, and studies.
Surgical Glove Compression to Prevent Paclitaxel Neuropathy: Randomized Trial
Sponsor: Necmettin Erbakan University
Summary
This study aims to evaluate the effect of surgical glove compression as a prophylactic method to prevent paclitaxel-induced peripheral neuropathy. Participants will be randomly assigned to two groups: one receiving standard care, and the other receiving prophylactic surgical glove compression. The study will compare the development, severity of neuropathy in the hands and fingers, and its impact on quality of life.
Official title: Comparison of Surgical Glove Compressions as a Prophylactic Method to Prevent Paclitaxel-induced Peripheral Neuropathy: Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
84
Start Date
2026-03-26
Completion Date
2027-03-26
Last Updated
2026-04-01
Healthy Volunteers
No
Interventions
Surgical glove compression during paclitaxel infusion
n the intervention group, each patient will wear two standard surgical gloves on the same single hand throughout the study (the first glove will be half a size smaller, the second glove one size smaller). The gloves will be worn 30 minutes before the paclitaxel infusion, during the infusion, and for 30 minutes after the infusion. This procedure will be performed each time the patient comes for treatment. No additional interventions will be applied besides the surgical gloves. The gloves must fit the patients' hands properly, and the study nurse will determine the appropriate glove size for each patient.
Locations (1)
Necmettin Erbakan University, Faculty of Health Sciences
Konya, Meram, Turkey (Türkiye)