Clinical Research Directory

Inclusion Criteria: * Cycloplegic spherical equivalent of \>-1.00D * Refractive cylinder -2.00 D or less; anisometropia \<1.00D * Best spectacle corrected visual acuity (BSCVA) of 6/12 or better in both eyes * Spherical or cylindrical error has progressed at -0.50 D or less per year from date of baseline measurement in both eyes * Contact lens wearers must have removed contact lenses at least 2 weeks before the baseline measurement * No evidence of irregular astigmatism on corneal topography in both eyes Exclusion Criteria: * Progressive or unstable myopia and/or astigmatism * Clinical or corneal topographic evidence of keratoconus * Residual, recurrent or active ocular disease such as uveitis, severe dry eyes, severe allergic eye disease, glaucoma, visually significant cataract, and retinal disease * Previous corneal surgery or trauma within the corneal flap zone * Patent corneal vascularization within 1 mm of the corneal flap zone * Taking systemic medications likely to affect wound healing, such as corticosteroids and antimetabolites * Systemically immunocompromised or systemic disease likely to affect wound healing, such as diabetes, connective tissue disease, and severe atopy; pregnant or nursing