Clinical Research Directory

Inclusion Criteria: * Adult patients with cytologically confirmed papillary thyroid carcinoma with the longest diameter of less than or equal to 10 mms in T1aN0M0 clinical stage without metastases and without cytological signs of aggressivity AND * Patients objecting to both surgery and active surveillance Exclusion Criteria: * History of or active disease: neck irradiation, stroke, CV disease, CNS vascular malformation, any malignant disease, immunocompromised state, recurrent laryngeal nerve paresis, organ failure * extrathyroidal extension of tumor (including capsular) * pregnancy * lesion less than 5 mm close to the danger zone * safety margin could not be obtained (min 2mm) * uncontrolled hyperthyroidism * uncontrolled hypothyroidism * primary hyperparathyroidism * calcitonin or serum calcium over the threshold on a repeat blood test