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Performance of the Treatment of Periodontitis According to the Bioperio® Protocol
Sponsor: University of Pisa
Summary
This multicenter, prospective, single-arm observational study evaluated the clinical performance of the Bioperio® protocol, a standardized, patient-centered framework for managing periodontitis. The protocol combined professional supra-gingival scaling, oral hygiene instruction and motivation, full-mouth subgingival instrumentation, and-in Stage III/IV cases-adjunctive enamel matrix derivative application in deep pockets.
Official title: Performance of the Treatment of Periodontitis According to the Bioperio® Protocol: a Prospective Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
5000
Start Date
2023-12-05
Completion Date
2030-12-05
Last Updated
2026-05-01
Healthy Volunteers
No
Conditions
Interventions
Periodontal non surgical treatment
Non surgical periodontal therapy performed with ultrasonics and manual instruments. In patients affected by stages III-IV periodontitis, the adjunctive usage of wound healing enhancers will be applied in sites with PPD \>5 mm.
Oral Hygiene Instructions
Patients will be motivated and instructed to improve their daily home dental plaque control through the usage of interdental devices and electric toothbrush.
Surgical Periodontal Treatment
In some selected patients, whose periodontal defects will not heal despite consecutive non surgical interventions, periodontal surgical treatment, with or without regenerative devices, will be implemented.
Locations (1)
University of Pisa
Pisa, None Selected, Italy