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Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy
Sponsor: Fayoum University Hospital
Summary
The original EXORA block used high local anesthetic volume (50 mL total), raising concerns about local anesthetic systemic toxicity (LAST). In such a bilaterally administered regional technique, evaluating the efficacy of a reduced-volume approach is warranted to maximize patient safety.
Official title: Analgesic Efficacy of Low-Volume Versus Standard-Volume 0.25% Bupivacaine for Ultrasound-Guided External Oblique and Rectus Abdominis Plane Block in Laparoscopic Cholecystectomy, A Randomized Non-Inferiority Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
96
Start Date
2026-04-12
Completion Date
2027-01-02
Last Updated
2026-09-02
Healthy Volunteers
No
Interventions
EXORA block 15
15 mL of bupivacaine 0.25% administered bilaterally by ultrasound guided EXORA block
EXORA block 25
25 mL of bupivacaine 0.25% administered bilaterally by ultrasound guided EXORA block
Locations (1)
Fayoum University hospital
El Fayoum Qesm, Faiyum Governorate, Egypt