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NOT YET RECRUITING
NCT07507955
NA

Probiotics for Constipation Relief in Adults

Sponsor: Wecare Probiotics Co., Ltd.

View on ClinicalTrials.gov

Summary

This study aims to evaluate the efficacy and safety of Bifidobacterium animalis subsp. lactis BLa36 in adults with functional constipation. In this randomized, double-blind, placebo-controlled trial, participants will receive BLa36 supplementation or placebo for 8 weeks. Clinical outcomes will be assessed using validated gastrointestinal symptom scales, stool characteristics, and quality-of-life measures. In addition, changes in inflammatory and immune markers, gut microbiota composition, metabolic indicators, and gut-brain axis-related parameters will be evaluated to comprehensively determine the effects of BLa36 on intestinal function and overall health.

Official title: To Evaluate the Efficacy and Safety of Probiotics in Alleviating Constipation in Adults Through a Randomized, Double-blind, Placebo-controlled Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

105

Start Date

2026-06-10

Completion Date

2027-01-20

Last Updated

2026-06-09

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Probiotic

BLa36 will be administered orally once daily for 8 weeks. Follow-up assessments will be conducted at Week 0, Week 4, and Week 8.

DIETARY_SUPPLEMENT

Maltodextrin

Maltodextrin will be administered orally once daily for 8 weeks. Follow-up assessments will be conducted at Week 0, Week 4, and Week 8.

DIETARY_SUPPLEMENT

High-activity probiotic group

BLa36 will be administered orally once daily for 8 weeks. Follow-up assessments will be conducted at Week 0, Week 4, and Week 8.

Locations (1)

Suzhou Ninth People's Hospital

Suzhou, Jiangsu, China