Clinical Research Directory
Browse clinical research sites, groups, and studies.
Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants: a Pilot Study
Sponsor: Baylor College of Medicine
Summary
The goal of this smaller clinical trial is to evaluate the study design of this research to help prepare for a larger research study in the future. The future larger study would focus on whether steroid cream can reduce recurrent urinary tract infections in male infants, who are not circumcised. Male infants, who are enrolled in this study, would receive either the steroid cream or a placebo cream (a look alike cream without steroids). The cream would be applied twice a week for four weeks. Then there would be two follow up visits with the research team to measure whether the infant experienced any urinary tract infections and to measure parent perceptions of their experience participating in the study.
Official title: Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants With a First Febrile Urinary Tract Infection: a Multi-center Pilot Study
Key Details
Gender
MALE
Age Range
0 Months - 5 Months
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2026-04
Completion Date
2027-12
Last Updated
2026-04-02
Healthy Volunteers
No
Conditions
Interventions
betamethasone valerate 0.1% cream
Steroid cream applied to the foreskin and glans twice a day for four weeks.
Placebo cream
Placebo cream is applied to the foreskin and glans twice a day for four weeks.
Locations (3)
Texas Children's Hospital Main campus
Houston, Texas, United States
Texas Children's Hospital West Campus
Katy, Texas, United States
Seattle Children's Hospital
Seattle, Washington, United States