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Risk Factors Affecting Growth in Thalassemic Children at AUCH
Sponsor: Assiut University
Summary
Thalassemia major is a hereditary hemoglobinopathy characterized by ineffective erythropoiesis and severe anemia, necessitating lifelong blood transfusions(1,2). Regular transfusions lead to iron overload, a primary driver of growth retardation in affected children. Iron accumulation in tissues like the pituitary and liver disrupts growth hormone secretion and insulin-like growth factor-1 production.
Official title: The Effect of Different Risk Factors on Growth Parameters of Thalassemic Patients in Assiut University Children Hospital
Key Details
Gender
All
Age Range
12 Months - 18 Years
Study Type
OBSERVATIONAL
Enrollment
85
Start Date
2026-04-01
Completion Date
2027-05-01
Last Updated
2026-04-03
Healthy Volunteers
Not specified
Interventions
Non-interventional assessment of growth and risk factors in thalassemic children
No therapeutic intervention is applied. The study involves only observational assessment of clinical history, anthropometric measurements, laboratory investigations, and growth parameters in thalassemic children. This distinguishes it from interventional studies.