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NOT YET RECRUITING
NCT07511569
NA

Prospective Exploratory Study of a Multiomic Blood Biomarker Panel to Predict Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Sponsor: Centre Hospitalier de Bligny

View on ClinicalTrials.gov

Summary

The goal of this prospective, multicenter, observational cohort study with longitudinal blood sampling and standardized neurological evaluation over 6 months is to identify biomarkers to predict the overall occurrence of chronic chemotherapy-induced peripheral neuropathy (CIPN, any grade), in each of two treatment subgroups (taxanes and oxaliplatin). It involves integration of clinical data and plasma multiomic biomarkers (proteomic + metabolomic panel) analyzed via supervised machine learning to identify predictive features of CIPN.

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

192

Start Date

2027-01-04

Completion Date

2029-06-04

Last Updated

2026-04-06

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

longitudinal blood sampling and standardized neurological evaluation over 6 months

Prospective, multicenter, observational cohort study with longitudinal blood sampling and standardized neurological evaluation over 6 months