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NOT YET RECRUITING
NCT07512297
PHASE4

Pain Control During ESWL Using Non-Opioid Analgesics

Sponsor: University of Gaziantep

View on ClinicalTrials.gov

Summary

This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL). All patients undergoing ESWL will be randomly assigned into four groups including a placebo group. Pain intensity will be assessed using the Visual Analog Scale (VAS) at the 5th, 10th, 15th, and 20th minutes during the procedure. In addition to comparing analgesic efficacy, the study will evaluate patient-related and stone-related factors affecting pain perception, including body mass index, subcutaneous fat thickness, and stone density measured by Hounsfield Units. The study also aims to assess the relationship between analgesic efficacy, energy levels applied during ESWL, and treatment outcomes such as stone-free rates. The findings may contribute to optimizing individualized pain management strategies and improving treatment efficiency in ESWL procedures.

Official title: Comparative Evaluation of Non-Opioid Analgesics for Pain Control During Extracorporeal Shock Wave Lithotripsy: A Prospective Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

160

Start Date

2026-04-01

Completion Date

2027-03-01

Last Updated

2026-04-09

Healthy Volunteers

No

Interventions

DRUG

Ibuprofen (Brufen®)

Ibuprofen administered prior to ESWL for pain control.

DRUG

Paracetamol (drug)

Paracetamol administered prior to ESWL for pain control.

DRUG

Tenoxicam

Tenoxicam administered prior to ESWL for pain control.

DRUG

Placebo

Placebo administered prior to ESWL.

Locations (1)

Gaziantep University Faculty of Medicine Hospital

Gaziantep, Turkey, Turkey (Türkiye)