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Pain Control During ESWL Using Non-Opioid Analgesics
Sponsor: University of Gaziantep
Summary
This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL). All patients undergoing ESWL will be randomly assigned into four groups including a placebo group. Pain intensity will be assessed using the Visual Analog Scale (VAS) at the 5th, 10th, 15th, and 20th minutes during the procedure. In addition to comparing analgesic efficacy, the study will evaluate patient-related and stone-related factors affecting pain perception, including body mass index, subcutaneous fat thickness, and stone density measured by Hounsfield Units. The study also aims to assess the relationship between analgesic efficacy, energy levels applied during ESWL, and treatment outcomes such as stone-free rates. The findings may contribute to optimizing individualized pain management strategies and improving treatment efficiency in ESWL procedures.
Official title: Comparative Evaluation of Non-Opioid Analgesics for Pain Control During Extracorporeal Shock Wave Lithotripsy: A Prospective Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2026-04-01
Completion Date
2027-03-01
Last Updated
2026-04-09
Healthy Volunteers
No
Conditions
Interventions
Ibuprofen (Brufen®)
Ibuprofen administered prior to ESWL for pain control.
Paracetamol (drug)
Paracetamol administered prior to ESWL for pain control.
Tenoxicam
Tenoxicam administered prior to ESWL for pain control.
Placebo
Placebo administered prior to ESWL.
Locations (1)
Gaziantep University Faculty of Medicine Hospital
Gaziantep, Turkey, Turkey (Türkiye)