Clinical Research Directory

Inclusion Criteria: * Adults aged 50-74 years * Active or former smoker having quit less than 15 years ago * Smoking history of at least 20 pack-years, or 15 cigarettes/day for 25 years or 10 cigarettes/day for 30 years * Affiliation with a social security scheme * Written informed consent prior to study participation Temporary exclusion Criteria * Chest CT scan performed within the previous 12 months * Signs of respiratory infection (fever, productive cough) Exclusion Criteria: * Severe co-morbidities contraindicating exploration and/or management (including stereotactic surgery or radiotherapy) of lung cancers * Poor general status (PS2 and above) * Rest dyspnea (mMRC4) * Cancer under active surveillance by thoracic computed tomography (CT pr PET-CT) * Personal history of lung cancer * Symptoms raising suspicion of lung cancer (hemoptysis, unexplained weight loss, recent onset or modification of respiratory symptoms,…)