Clinical Research Directory
Browse clinical research sites, groups, and studies.
Study of a Polygenic Risk Score to Predict the Risk of Pancreatic Ductal Adenocarcinoma
Sponsor: Catholic University of the Sacred Heart
Summary
This case-control study aims to evaluate the role of a polygenic risk score in predicting the risk of pancreatic ductal adenocarcinoma (PDAC). The study will compare genetic risk profiles between individuals with PDAC and controls without the disease in order to assess whether a polygenic risk score may help identify individuals at higher risk. The findings may contribute to improving risk stratification and supporting future strategies for early identification and prevention of pancreatic cancer.
Official title: PRE-PDAC: Evaluation of Polygenic Risk scorE for Pancreatic Ductal AdenoCarcinoma Risk Prediction: a Case-control Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1140
Start Date
2026-04-01
Completion Date
2026-09-30
Last Updated
2026-04-08
Healthy Volunteers
Yes
Conditions
Interventions
Blood sample collection
Blood sample collection for biomarker and genetic analysis. Peripheral blood samples are collected from participants and used for laboratory analyses, including genotyping, biomarker assessment, and evaluation of polygenic risk score-based models for pancreatic ductal adenocarcinoma risk prediction.