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The Effects of Acute Erythropoietin on Hepcidin and Dietary Iron Absorption Following Military-relevant Exercise in Energy Deficit: Pilot Study
Sponsor: Pennington Biomedical Research Center
Summary
Military personnel frequently experience declines in iron status during training and when in the field, which may compromise performance. The overall purpose of this study is to determine why the decline in iron status occurs and potential countermeasures. Participants will be given an acute dose of erythropoietin (EPO) or placebo and will complete a 90-minute load carriage exercise test. Prior to the main trial, this pilot study will determine the optimal approach to assess iron absorption following exercise (red blood cell incorporation or plasma isotope appearance), the percentage of iron incorporated into red blood cells with EPO compared to placebo, and the timing of the intervention.
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
6
Start Date
2025-09-01
Completion Date
2026-05-01
Last Updated
2026-04-08
Healthy Volunteers
Yes
Conditions
Interventions
Exercise test
90-minute load carriage exercise test on a treadmill
Locations (1)
LSU Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States