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Serum Bicarbonate and Enteral Feeding Intolerance in Adult ICU: A Prospective Clinical Trial
Sponsor: Istinye University
Summary
This prospective, observational study evaluates whether serum bicarbonate HCO3 levels can predict enteral nutrition intolerance (EFI) in adult ICU patients.Objective: To determine if lower HCO3 levels correlate with the development of EFI.Design: A 12-month study involving 70 participants at Sultangazi Haseki Training and Research Hospital.Methodology: Patients starting enteral nutrition within 48 hours of admission will be monitored for 72 hours. Daily HCo3 pH, and lactate levels will be recorded from routine morning blood draws.Hypothesis: Lower bicarbonate levels are an independent predictor of EFI development in critically ill patients.
Official title: Serum Bicarbonate and Enteral Feeding Intolerance in Adult ICU Patients: A Prospective Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2026-04-15
Completion Date
2027-01-15
Last Updated
2026-04-08
Healthy Volunteers
No
Conditions
Interventions
Enteral Nutrition Intolerance (EFI)
The study investigates the development of EFI, characterized by symptoms like increased gastric residual volume, vomiting, and abdominal distension.
Locations (1)
Istinye Üniversity
Istanbul, Merkez Mahallesi, Turkey (Türkiye)