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Pre-Extubation Bupivacaine for Pain Control After Orthognathic Surgery
Sponsor: Esra Beyler
Summary
This study aims to evaluate whether injecting a long-acting local anesthetic (bupivacaine) at surgical sites before awakening from anesthesia can reduce pain and the need for opioid medications after orthognathic surgery. Orthognathic surgery is a major procedure that can cause significant postoperative pain, often requiring opioid analgesics, which may lead to side effects such as nausea, vomiting, and drowsiness. In this randomized clinical study, patients undergoing jaw surgery received either standard care or additional bupivacaine infiltration before extubation. Pain levels and opioid consumption were measured during the first 48 hours after surgery. We hypothesized that pre-extubation bupivacaine infiltration would improve pain control and reduce opioid requirements.
Official title: Effect of Pre-extubation Bupivacaine Infiltration on Postoperative Pain and Opioid Consumption After Orthognathic Surgery
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
102
Start Date
2022-09-02
Completion Date
2025-09-02
Last Updated
2026-04-21
Healthy Volunteers
No
Conditions
Interventions
Bupivacaine Infiltration
Pre-extubation local infiltration of 0.5% bupivacaine with epinephrine was administered at the surgical sites in addition to standard perioperative care
Standard medical treatment
Patients received standard perioperative care without pre-extubation bupivacaine infiltration
Locations (1)
Baskent University
Ankara, Cankaya, Turkey (Türkiye)