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ENROLLING BY INVITATION
NCT07520175

A Study of Outcomes Following Bio-Reinforced Canaloplasty in Eyes With Open-Angle Glaucoma

Sponsor: Iantrek, Inc.

View on ClinicalTrials.gov

Summary

The goal of this study is to learn about outcomes after bio-reinforced canaloplasty surgery to enhance aqueous outflow in patients with OAG. The key question the study aims to answer is: How much does the surgical procedure lower pressure inside the eye and what is the durability of this effect? Participants will return for periodic eye exams for 2 years following surgery.

Official title: An Observational Study of Safety and Effectiveness Outcomes Following Bio-Reinforced Canaloplasty for Trabecular Outflow Enhancement in Eyes With Open-Angle Glaucoma (The BOOST Study)

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2026-04-01

Completion Date

2029-12

Last Updated

2026-05-22

Healthy Volunteers

No

Interventions

PROCEDURE

AlloSpan Canal Platform Bio-Reinforced Canaloplasty

Bio-reinforced canaloplasty using the AlloSpan Canal Platform is a gonio-interventional approach to enhance trabecular outflow. Standard gonio-positioning of the microscope and the head is involved. A clear corneal incision is performed temporally. The anterior chamber is filled with viscoelastic and the angle is expanded and visualized to identify the gonio-structures. An entry gonio-puncture of the trabecular meshwork is performed to enter the canal and canaloplasty is performed with intraluminal dilation. After canaloplasty, a segmental canal scaffolding implant consisting of allograft scleral tissue is deployed for sustained canal reinforcement and dilation.

Locations (5)

Ridge Eye Care, Inc.

Chico, California, United States

North Bay Eye Associates

Petaluma, California, United States

Scott & Christie and Associates

Cranberry Township, Pennsylvania, United States

Key Whitman Eye Center

Dallas, Texas, United States

El Paso Eye Surgeons

El Paso, Texas, United States