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Effect of Antiemetic Timing on Nausea Severity and Patient Comfort in the Emergency Department
Sponsor: muzeyyen ataseven
Summary
Nausea is a common symptom among patients presenting to the emergency department and can negatively affect patient comfort and clinical outcomes. The timing of antiemetic administration may play a critical role in symptom control; however, evidence regarding the optimal timing remains limited. This multicenter interventional study aims to evaluate the effect of early versus delayed antiemetic administration on nausea severity and patient comfort in adult emergency department patients. Participants will be assigned to receive antiemetic treatment either within the first 30 minutes after triage or after 30 minutes. Nausea severity will be assessed using a numeric rating scale, and patient comfort will be evaluated at predefined time points. The findings of this study are expected to contribute to improving symptom management and optimizing clinical practices in emergency care settings.
Official title: The Effect of Antiemetic Timing on Nausea Severity and Patient Comfort in the Emergency Department: A Multicenter Interventional Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-02-05
Completion Date
2026-04-05
Last Updated
2026-04-27
Healthy Volunteers
No
Conditions
Interventions
Antiemetic Timing
The intervention consists of adjusting the timing of routine antiemetic administration in emergency department patients without altering the type or dosage of medication. Participants are assigned to receive antiemetics either within 30 minutes (early group) or after 30 minutes (delayed group) following triage (T0), in accordance with standard clinical care. Outcome measures include nausea severity assessed using a Numeric Rating Scale (NRS, 0-10) at T0, Tpost30, and Tpost60, and comfort level assessed at T0 and Tpost60.
Locations (1)
Istanbul Medipol University Hospital, Emergency Department
Istanbul, Turkey (Türkiye)