Clinical Research Directory

Inclusion Criteria: * Patients who have been intubated and receiving invasive mechanical ventilation for at least 24 hours in the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital and who are considered by the intensive care physician to be ready for weaning from mechanical ventilation: * Patients over 18 years of age * Patients who have given their voluntary consent Exclusion Criteria: * Patients under 18 years of age * Patients with a history of oral cavity surgery such as direct laryngoscopy and biopsy, microlaryngoscopic surgery, tonsillectomy, adenoidectomy, soft palate, oropharynx, hypopharynx, larynx and trachea, * Patients with a history of allergy, asthma, reflux, upper respiratory tract viral or fungal infections, and cancer surgery, * Patients who received radiotherapy to the neck region, or who had more than one intubation attempt in the previous year, * Tracheostomized patients, patients with upper respiratory tract obstruction, vocal cord paralysis, and patients with stridor clinical picture before intubation, * Patients for whom voluntary consent cannot be obtained