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RECRUITING
NCT07524114

Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

Sponsor: University Health Network, Toronto

View on ClinicalTrials.gov

Summary

This study will collect, annotate, and sequence biospecimens (blood, tissue, urine, saliva and surgery drainage) from patients across different cancer types to detect molecular residual disease (MRD). Imaging scans and clinical data will also be gathered. This will allow for early cancer interception, and hopefully prolong relapse-free survival across tumor types. Results of ctDNA testing will be provided for clinical decisions and to determine eligibility for other linked interventional interception therapeutic studies, each of which will have a separate protocol.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

7000

Start Date

2026-03-31

Completion Date

2031-03-31

Last Updated

2026-08-21

Healthy Volunteers

No

Locations (1)

Princess Margaret Hospital

Toronto, Ontario, Canada