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COMPLETED
NCT07524153

Diode Laser and S100A8 in Peri-Implantitis

Sponsor: Kırıkkale University

View on ClinicalTrials.gov

Summary

Purpose: The aim of this study was to compare the effectiveness of diode laser and combined treatment protocols, applied in addition to mechanical debridement, in the treatment of peri-implantitis on clinical periodontal parameters and S100A8 levels in peri-implant sulcus fluid (PISF). Methods: A total of 39 patients diagnosed with peri-implantitis were divided into three groups based on the treatment protocols used: Mechanical Debridement, Diode Laser, and Combined Treatment. Probing depth, clinical attachment level, modified plaque index, gingival index, and PISF volume measurements were recorded at baseline and at weeks 4 and 12. S100A8 levels in PISF samples were measured by ELISA.

Official title: Effect of 940 nm Diode Laser as an Adjunct to Mechanical Debridement on S100A8 Levels and Clinical Parameters in Peri-Implantitis Treatment

Key Details

Gender

All

Age Range

30 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

39

Start Date

2025-01-01

Completion Date

2025-10-10

Last Updated

2026-04-13

Healthy Volunteers

Yes

Locations (1)

Kırıkkale University, Faculty of Dentistry

Kırıkkale, Kırıkkale, Turkey (Türkiye)