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Nigella Sativa Oil for Eczematous Otitis Externa
Sponsor: Bezmialem Vakif University
Summary
Eczematous otitis externa is a common inflammatory condition of the external auditory canal characterized by itching, discomfort, discharge, and pain. Topical corticosteroids are widely used for treatment; however, alternative therapies with fewer side effects are of increasing interest. This study aims to compare the efficacy of Nigella sativa (black seed) oil and mometasone furoate ear drops in the treatment of eczematous otitis externa. Nigella sativa is a natural product with known anti-inflammatory and antimicrobial properties. In this randomized, controlled clinical trial, adult patients with eczematous otitis externa will be assigned to receive either Nigella sativa oil or mometasone furoate ear drops for 10 days. Clinical symptoms and inflammatory findings will be evaluated at baseline and after treatment. The objective of this study is to determine whether Nigella sativa oil is an effective and safe alternative to topical corticosteroid therapy.
Official title: Efficacy of Nigella Sativa Oil in Eczematous Otitis Externa: A Randomized Controlled Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
85
Start Date
2026-01-12
Completion Date
2026-07
Last Updated
2026-04-21
Healthy Volunteers
No
Conditions
Interventions
Mometasone Furoate (MF)
Topical corticosteroid solution administered as ear drops (2 drops twice daily for 10 days).
Nigella sativa oil
A fixed oil obtained from Nigella sativa seeds, administered as ear drops (2 drops twice daily for 10 days).
Locations (1)
Bezmialem Vakif University
Istanbul, Fatih, Turkey (Türkiye)