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RECRUITING
NCT07525505
NA

Nigella Sativa Oil for Eczematous Otitis Externa

Sponsor: Bezmialem Vakif University

View on ClinicalTrials.gov

Summary

Eczematous otitis externa is a common inflammatory condition of the external auditory canal characterized by itching, discomfort, discharge, and pain. Topical corticosteroids are widely used for treatment; however, alternative therapies with fewer side effects are of increasing interest. This study aims to compare the efficacy of Nigella sativa (black seed) oil and mometasone furoate ear drops in the treatment of eczematous otitis externa. Nigella sativa is a natural product with known anti-inflammatory and antimicrobial properties. In this randomized, controlled clinical trial, adult patients with eczematous otitis externa will be assigned to receive either Nigella sativa oil or mometasone furoate ear drops for 10 days. Clinical symptoms and inflammatory findings will be evaluated at baseline and after treatment. The objective of this study is to determine whether Nigella sativa oil is an effective and safe alternative to topical corticosteroid therapy.

Official title: Efficacy of Nigella Sativa Oil in Eczematous Otitis Externa: A Randomized Controlled Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

85

Start Date

2026-01-12

Completion Date

2026-07

Last Updated

2026-04-21

Healthy Volunteers

No

Interventions

DRUG

Mometasone Furoate (MF)

Topical corticosteroid solution administered as ear drops (2 drops twice daily for 10 days).

DRUG

Nigella sativa oil

A fixed oil obtained from Nigella sativa seeds, administered as ear drops (2 drops twice daily for 10 days).

Locations (1)

Bezmialem Vakif University

Istanbul, Fatih, Turkey (Türkiye)