Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery
Sponsor: Medipol University
Summary
Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP). Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP. This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.
Official title: Comparison of the Effects of Sevoflurane and Desflurane Used for Anesthesia Maintenance on Optic Nerve Sheath Diameter in the Trendelenburg Position
Key Details
Gender
FEMALE
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-04-15
Completion Date
2026-05-15
Last Updated
2026-04-13
Healthy Volunteers
No
Interventions
Sevoflurane
Anesthesia maintenance will be provided with sevoflurane at 1 MAC in a 40% oxygen-air mixture.
Desflurane
Anesthesia maintenance will be provided with desflurane at 1 MAC in a 40% oxygen-air mixture.
Locations (1)
Istanbul Medipol University
Istanbul, Turkey (Türkiye)