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Physiology-Guided Airway Preparation Enhances Hemodynamics and Cerebral Oxygenation
Sponsor: Prince Sultan Military Medical City
Summary
This study looked at a safer way to prepare patients for anesthesia before major spinal surgery. Instead of using advanced or complex oxygen devices, the approach used standard oxygen methods, guided by the patient's individual physiological responses (such as oxygen levels and circulation).
Official title: Physiology-Guided Airway Preparation Using Standard Oxygen Therapy Improves Hemodynamic Stability and Cerebral Oxygenation During Induction of Anesthesia for Major Spinal Surgery: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
90
Start Date
2026-04-10
Completion Date
2026-08-30
Last Updated
2026-04-16
Healthy Volunteers
No
Interventions
regional cerebral oxygen saturation
By employing multi-wavelength technology on the forehead, the O3 device provides clinicians with crucial insights into the balance between cerebral oxygen demand and supply. This monitoring is especially valuable for high-risk patient populations, such as those undergoing cardiac surgery, and patients in the intensive care unit (ICU), which provides a continuous, non-invasive assessment of rSO₂ enabling the prompt detection of critical desaturation events. Crucially, changes in rSO₂ during induction correlate with factors directly relevant to spinal cord safety, such as hypotension, hypocapnia, and reduced cardiac output.
Locations (1)
Prince Sultan Military Medical City
Riyadh, Saudi Arabia