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Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder
Sponsor: Tanta University
Summary
This study aimed to compare the efficacy, safety, and tolerability of electroconvulsive therapy (ECT) versus intravenous (IV) ketamine in adults with treatment-resistant major depressive disorder (TRD).
Official title: Comparative Efficacy of Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2025-07-01
Completion Date
2026-02-01
Last Updated
2026-04-13
Healthy Volunteers
No
Interventions
Electroconvulsive Therapy
Patients received Bitemporal electroconvulsive Therapy (ECT) (2x/week for 4 weeks).
Ketamine
Patients received intravenous (IV) ketamine 0.5 mg/kg IV infusion over 40 mins (2x/week for 4 weeks).
Locations (1)
Tanta University
Tanta, El-Gharbia, Egypt