Clinical Research Directory

Inclusion Criteria: 1. Pregnant women aged 18 to 45 years with singleton pregnancy; 2. For maternal groups: diagnosed with heart disease (congenital, valvular, or cardiomyopathy) or healthy without cardiac disease; 3. For fetal groups: diagnosed with congenital heart disease, anti-Ro/SSA antibody positive status, or normal cardiac structure; 4. Able to cooperate with non-invasive monitoring and follow-up procedures; 5. Voluntary written informed consent provided prior to enrollment. Exclusion Criteria: 1. Multiple pregnancy; 2. Severe skin disease or thoracic deformity preventing placement of monitoring sensors; 3. History of malignancy, severe hepatic or renal dysfunction; 4. Inability to complete follow-up visits or monitoring; 5. Contraindications to non-invasive monitoring procedures.