Clinical Research Directory
Browse clinical research sites, groups, and studies.
Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure
Sponsor: Institute for Clinical and Experimental Medicine
Summary
This study will evaluate the feasibility and safety of achieving therapeutic concentrations of beta-hydroxybutyrate using continuous infusion of D-beta-hydroxybutyrate monoester administered via a nasogastric tube in patients with acutely decompensated heart failure with reduced left ventricular ejection fraction.
Official title: Feasibility and Safety of Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2026-04-04
Completion Date
2027-03-31
Last Updated
2026-04-14
Healthy Volunteers
No
Interventions
Ketone Monoester (KE)
Continous infusion of a commercially available ketone monoester via nasogastric tube.
Locations (1)
Institute for Clinical and Experimental Medicine (IKEM)
Prague, Prague, Czechia