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Comparison of Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Prophylaxis of PDPH in Patients With History of PDPH.
Sponsor: Sargodha Medical College
Summary
It is hypothesized that there is a difference between intravenously administered aminophylline with intravenous acetaminophen and intravenously administered aminophylline with dexamethasone for prevention of and reducing severity of PDPH.
Official title: Comparison of Prophylactic Intravenous Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Post Dural Puncture Headache Prevention in Surgical Patients With History of PDPH
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-08-01
Completion Date
2024-07-08
Last Updated
2026-04-14
Healthy Volunteers
No
Conditions
Interventions
Inj Aminophylline 100mg with Inj Acetaminophen 1000mg in 100ml Normal Saline
This group will receive Inj. Aminophylline 100mg as slow IV. Infusion over 30 minutes followed by inj. Acetaminophen 1000mg in 100 ml Normal saline solution as slow infusion.
Inj Aminophylline 100mg , with 0.1mg/kg Dexamethasone in 100ml Normal Saline
This group will receive Inj. Aminophylline 100mg as slow IV infusion over 30minutes followed by 0.1mg/kg dexamethasone in 100ml Normal saline IV infusion.
Locations (1)
Dr.Faisal Masood Teaching Hospital, Sargodha
Sargodha, Punjab Province, Pakistan