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Novel 3-dimensional Echocardiographic Quantification of Mitral Regurgitant Volume
Sponsor: Germans Trias i Pujol Hospital
Summary
The goal of this observational study is demonstrate that a novel artificial intelligence based software for the quantification of the mitral regurgitation on 3-dimensional transesophageal echocardiography (3D CFQ) is more reproducible and accurate than the conventional assessment of mitral regurgitation performed with 2-dimensional echocardiography. The main question aims to answer is to demonstrate the agreement between 3D-CFQ measurement of the mitral regurgitant volume and the cardiac magnetic resonance measurement of the regurgitant volume is better than the agreement between 2-dimensional echocardiography and cardiac magnetic resonance. If this is demonstrated, we would like to test the accuracy of this tool to be applied in acute settings such as transcatheter interventions to decide the therapy to follow. Participants will undergo clinically indicated transesophageal echocardiography to characterize the mechanism and severity of mitral regurgitation and to cardiac magnetic resonance to be used as reference stadard to define the mitral regurgitation severity.
Key Details
Gender
All
Age Range
18 Years - 95 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2026-03-17
Completion Date
2028-04-01
Last Updated
2026-04-14
Healthy Volunteers
No
Conditions
Interventions
analysis of the performance of an artificial intelligenced based software for analysis of 3D tranesophageal echocardiography data
The analysis of mitral regurgitation in current practice is based on multiparametric approach of several 2-dimensional Doppler echocardiographic parameters and quantification of mitral regurgitant volume and effective regurgitant orifice area measured with the proxymal isovelocity surface area. This novel algorithm based on artificial intelligence based software may change clinical practice if demonstrates that provides more accurate estimation of the severity of mitral regurgitation.
Locations (1)
Hospital University Germans Trias i Pujol
Badalona, Barcelona, Spain