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Clinical Application of 89Zr-s-C1 PET/CT Imaging in Solid Tumors
Sponsor: Peking University Cancer Hospital & Institute
Summary
This project is driven by clinical needs and focuses on the mucin (MUC) family, key glycopeptide antigens involved in mediating immune evasion in solid tumors. We selected multiple members of this family as research subjects. Based on the MUC18 target, we developed the probe ⁸⁹Zr-SS-CNB001 (HuAA98-14, hereafter referred to as ⁸⁹Zr-s-C1). Studies have demonstrated that ⁸⁹Zr-s-C1 PET/CT enables noninvasive in vivo identification of tumor lesions in patients with solid tumors, and its imaging efficacy positively correlates with MUC18 expression levels in the patient's tumor tissue.
Key Details
Gender
All
Age Range
15 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2026-04-14
Completion Date
2028-03-01
Last Updated
2026-04-14
Healthy Volunteers
No
Conditions
Locations (1)
Beijing cancer hosipitaal
Beijing, Beijing Municipality, China