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RECRUITING
NCT07529145

Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment

Sponsor: Medical University of Bialystok

View on ClinicalTrials.gov

Summary

Patients with lung cancer often have reduced physical fitness and coexisting health problems, which may limit their ability to tolerate oncological treatment. Standard resting lung and heart tests do not always reflect real-life physical capacity during everyday activities or physical effort. This observational study aims to assess cardiorespiratory fitness in patients with lung cancer before and during standard oncological treatment using cardiopulmonary exercise testing (CPET). CPET is a safe, supervised exercise test that provides objective information on how the heart, lungs, and muscles respond to physical effort. Participants with WHO/ECOG performance status 0-2 will undergo CPET before treatment initiation and again after the early phase of therapy or surgery. The results may help identify patients with reduced physiological reserve and support individualized monitoring during routine clinical care.

Official title: Assessment of Respiratory Parameters and Physical Performance in Patients With Lung Cancer Qualified for Oncological Treatment Before and During Therapy, With Special Consideration of Cardiovascular Risk: A Cardiopulmonary Exercise Testing Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

90

Start Date

2026-01-01

Completion Date

2027-09-01

Last Updated

2026-04-14

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Cardiopulmonary Exercise Testing (CPET)

Symptom-limited cardiopulmonary exercise testing performed using a standardized incremental protocol on a cycle ergometer to assess integrated cardiorespiratory, ventilatory, and metabolic responses to exercise. The test is conducted under continuous medical supervision with electrocardiographic and blood pressure monitoring, in accordance with established safety guidelines and standard termination criteria.

Locations (1)

University Clinical Hospital in Bialystok, II Department of Pulmonology, Lung Cancer and Internal Medicine, Medical University of Bialystok

Bialystok, Podlaskie Voivodeship, Poland