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RECRUITING
NCT07529626

Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer

Sponsor: Shanghai Zhongshan Hospital

View on ClinicalTrials.gov

Summary

This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer. Researchers will ask participants to fill out simple questionnaires about their mood, worries, and sleep at the start of the study and at regular follow-up visits. The study will also collect a small blood sample (leftover from routine care) to measure stress-related markers. Investigators hypothesize that pancreatic cancer patients who have higher levels of ongoing psychological stress (such as anxiety, depression, or poor sleep) tend to have shorter survival times, a higher chance of recurrence, and a poorer response to treatment, compared to patients with lower stress levels.

Official title: A Prospective Cohort Study on the Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer: A Comprehensive Analysis Based on Multidimensional Dynamic Psychological Assessment (MIND-PANC)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

320

Start Date

2026-05-11

Completion Date

2028-12-31

Last Updated

2026-06-29

Healthy Volunteers

No

Locations (3)

the Third Xiangya Hospital of Central South University

Changsha, Hunan, China

Zhongshan Hospital Affiliated to Fudan University

Shanghai, Shanghai Municipality, China

The First Affiliated Hospital of Xi'an Jiao Tong University

Xi’an, Shanxi, China