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Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer
Sponsor: Shanghai Zhongshan Hospital
Summary
This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer. Researchers will ask participants to fill out simple questionnaires about their mood, worries, and sleep at the start of the study and at regular follow-up visits. The study will also collect a small blood sample (leftover from routine care) to measure stress-related markers. Investigators hypothesize that pancreatic cancer patients who have higher levels of ongoing psychological stress (such as anxiety, depression, or poor sleep) tend to have shorter survival times, a higher chance of recurrence, and a poorer response to treatment, compared to patients with lower stress levels.
Official title: A Prospective Cohort Study on the Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer: A Comprehensive Analysis Based on Multidimensional Dynamic Psychological Assessment (MIND-PANC)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
320
Start Date
2026-05-11
Completion Date
2028-12-31
Last Updated
2026-06-29
Healthy Volunteers
No
Locations (3)
the Third Xiangya Hospital of Central South University
Changsha, Hunan, China
Zhongshan Hospital Affiliated to Fudan University
Shanghai, Shanghai Municipality, China
The First Affiliated Hospital of Xi'an Jiao Tong University
Xi’an, Shanxi, China